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Infecção Hospitalar por Staphylococcus aureus e Fatores de Risco para o Desenvolvimento da Síndrome do Choque Tóxico (Tsst-1) – Artigo de Revisão

DOI: http://dx.doi.org/10.15601/2238-1945/pcnb.v2n3p27-37

http://www3.izabelahendrix.edu.br/ojs/index.php/bio/index 

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Ricardo S. Dias1 & Paola C. Uccoli2

 

Resumo: Staphylococcus spp tem sido responsável por uma série de infecções que acometem o homem, as implicações clínicas são geralmente graves principalmente devido aos fatores de virulência e a elevada resistência a antimicrobianos apresentada por determinadas linhagens. A Síndrome do choque tóxico destaca-se como doença grave pois a enfermidade é causada por uma toxina denominada TSST-1 que apresenta atividade superantigênica, responsável pelos sinais e sintomas característicos. No Brasil são poucos os estudos sobre as causas que levam ao desenvolvimento do choque tóxico. Assim, esta revisão de literatura abordará temas referentes ao micro-organismo e a TSST-1 proporcionando aos profissionais de saúde informações que possam subsidiar as medidas e estratégias de tratamento e prevenção efetivas no controle da síndrome do choque tóxico relacionada às infecções causadas por Staphylococcus,

Palavras-chave: Staphylococcus, Síndrome do Choque Tóxico, infecção hosptalar

 

Abstract: Staphylococcus spp is responsible for a series of infections that affect human beings. Clinical implications are usually serious mainly due to its higher virulence factors and antimicrobial resistance by certain strains. The toxic shock syndrome is highlighted as serious illness, because the disease is caused by a toxin called TSST-1 that has a superantigenic activity and it is responsible for particular characteristic signs and symptoms. In Brazil there are few studies of the causes that lead to the toxic shock development. Thus, this review will discuss topics related to the analysed microorganism and TSST-1, providing information to health professionals which can provide actions and strategies for effective treatment and prevention in the control of toxic shock syndrome related to infections caused by Staphylococcus.

Key words: Staphylococcus; toxic shock syndrome; nosocomial infection

 

1 Biólogo, Doutor em Microbiologia, Professor do Centro Universitário Izabela Hendrix (CEUNIH). Membro da Sociedade Brasileira de Microbiologia – SBM. Pesquisador do Laboratório de Enterotoxinas- LACEN-FUNED. BH-MG. email: ricardo.dias@funed.mg.gov.br ricardo.dias@izabelahendrix.edu.br
2 Biomédica, Graduanda do Curso de Farmácia –Faculdade Pitágoras- BH-MG, Estagiária da FUNEDMG - Laboratório de Enterotoxinas.

 

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